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Wednesday, November 4, 2009

DNA Folding (School revision)


1) Firstly, the long strand double helix DNA coil a few rounds around the octomer histones. The octomer histones are positively charged.
2) In order to stabilise the DNA being uncoiled from the octomer histone, another protein called the H1 histone will attached onto the DNA and the octomer like a scotch tape, to stabilise it. The ending product is called nucleosome.
3) DNA continued to form more and more nucleosomes. After that, these nucleosomes in a long chain will coil itself like a spring shape. It will then be known as solenoid.
4) The solenoid then attach to another protein called scaffold to form loops. That is called the loop solenoid.
5) It then made up into chromosomes.

(WARNING: Information may be incorrect. If there are any incorrect information, or anything more to add, please give comments. )